mySQL to utf8mb4

I have added these line to /etc/mysql/my.cnf But I am getting error during creation of a site

character-set-server=utf8mb4
collation-server = utf8mb4_unicode_ci
init-connect='SET NAMES utf8mb4'
init_connect='SET collation_connection = utf8mb4_unicode_ci'
skip-character-set-client-handshake

Where is the error?